Arsenal beat Celta Vigo 2-0 with two first half goals by Thierry Henry for a 5-2 aggregate success to progress to the Champion's League quarter final tonight.
They were joined in the last eight by Real Madrid, who beat Bayern Munich 1-0 with a goal from Zinedine Zidane for a 2-1 aggregate win.
European champions AC Milan pulled back from the brink of elimination to beat Sparta Prague 4-1 and AS Monaco beat Lokomotiv Moscow 1-0 to squeeze through on the away goals rule after losing the first leg in Moscow 2-1.
Dado Prso scored Monaco's winner after 60 minutes to make amends for a penalty miss in the first half.
Wednesday's winning quartet will go into Friday's quarter-final draw with Porto, Chelsea, Olympique Lyon and Deportivo Coruna who all qualified on Tuesday night.
AC Milan briefly had one foot out of the exit door after Sparta substitute Tomas Jun scored two minutes after coming on to put Sparta level at 1-1 in the match - and ahead on away goals after the 0-0 draw in the first leg two weeks ago.
Milan endured a nervous seven minutes before Andriy Shevchenko put them 2-1 up with a well-taken header.
Thirteen minutes later he made it 3-1 and Gennaro Gattuso completed the scoring five minutes from time.
Filippo Inzaghi had scored Milan's opener on the stroke of halftime.