The Criminal Assets Bureau and the Northern Ireland Assets Recovery Agency (ARA) have seized more than £500,000 sterling (€748,216) from loyalist drug dealing in Belfast and fuel smuggling and laundering in south Armagh.
The agencies joined forces to crack down on a criminal network allegedly involved in cross-border fuel smuggling.
The ARA revealed it had won an injunction in the High Court last week to freeze assets of some £320,000 that it said were "in the possession of an individual in the south Armagh area and allegedly linked to fuel smuggling."
The CAB confirmed it had taken action in the against the same "criminal network".
The ARA also said it had won a second injunction freezing assets to the value of £240,000 in the possession of individuals in the East Belfast area. It said the case was linked to "alleged drug trafficking and loyalist paramilitary activity".
The granting of the orders by the High Court is a preliminary step to protect assets while the agency completes its investigations and formally applies to the court for Recovery Orders. If such orders are granted then all or part of the frozen assets will be forfeited.
Northern Ireland security minister Ms Jane Kennedy, chair of the Organised Crime Taskforce, paid tribute to the Assets Recovery Agency saying it was striking fear into criminals.
Since it had begun operations 12 months ago it had "enjoyed unprecedented success in stripping criminals of the profits from their crimes," she said.