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Systemic Lupus Erythematosus

Systemic Lupus Erythematosus

I have been diagnosed with Lupus, which I've been told is an autoimmune condition. Can you explain just what exactly is meant by this?

In autoimmune disorders, the body produces antibodies that attack its own tissues. Many autoimmune disorders affect the connective tissue. Systemic Lupus Erythematosus, known also as Lupus or SLE, is a chronic inflammation of connective tissue that can affect the blood, skin, joints, kidneys, heart, brain and lymphatic system, in any combination. Triggers for the condition are not yet known but some cases can be induced by drugs used to treat heart disease and tuberculosis.

My symptoms have been vague and changeable.How can my doctor be sure SLE is what I have?

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The symptoms of SLE are numerous and varied at the start of the illness, and this can make a definitive diagnosis more difficult. SLE often starts with a combination of complaints which include fatigue, weakness, painful joints, fever and rashes. Later a red, butterfly shaped rash develops over the nose and cheeks, sometimes accompanied by skin rashes on other parts of the body. Sensitivity to sunlight, mouth sores and joint inflammation are not uncommon. Problems with the heart, lungs, kidney and brain may also develop.

Will I always have it?

SLE tends to be a chronic and relapsing condition. Often sufferers will have symptom-free periods that can last from several months to years. More common in women, flare-ups tend to occur less often after menopause. In addition to the condition being diagnosed at an earlier stage, advancements in treatment have improved prognosis. Treatment will depend on the systems affected. Mild SLE may need no more than a simple anti-inflammatory drug to relieve joint pain, while more severe cases will require corticosteroids and other medications.

• More information is available from the Irish Lupus Support Group at 01-8724518.