Ryan Giggs is out of Manchester United's Premiership clash at Leeds tomorrow and could miss the Champions League clash against Panathinaikos next Wednesday.
The Welsh star has been under treatment for a hamstring problem since limping out of United's game against Valencia last week and Sir Alex Ferguson has ruled him out of his plans for the Saturday morning trip to Elland Road.
With Roy Keane doubtful after pulling out of the Republic of Ireland's midweek international against Denmark with fluid on the knee and England striker Andy Cole sitting out the second game of a three match ban, United are preparing to go into the clash with their rivals without three key players.
Before naming his line-up Ferguson will also check on Sunday hat-trick hero Dwight Yorke who has flown to Jamaica and back to play for Trinidad and Tobago in a World Cup qualifier since the 6-1 win over Arsenal which opened up United's lead at the top to 16 points,.
Leading scorer Teddy Sheringham, who came on as a late substitute on Sunday to grab his 19th goal of the season, could be in the starting line-up alongside Ole Gunnar Solskjaer.