Scotland coach Ian McGeechan has moved Brendan Laney from inside-centre to outhalf for the first time at international level.
Out-half Gordon Ross and outside centre Andy Craig have been dropped for the game against France following last week's 36-6 defeat by Ireland.
Gregor Townsend is recalled at outside centre with Kevin Utterson winning his first cap at inside centre.
McGeechan has also switched wingers Chris Paterson and Kenny Logan.
Scotland:15 Glenn Metcalfe (Glasgow Rugby), 14 Chris Paterson (Edinburgh Rugby), 13 Gregor Townsend (The Borders), 12 Kevin Utterson (The Borders), 11 Kenny Logan (London Wasps), 10 Brendan Laney (Edinburgh Rugby), Bryan Redpath (Sale Sharks, capt), 8 Simon Taylor (Edinburgh Rugby), 7 Andrew Mower (Newcastle Falcons), 6 Martin Leslie (Edinburgh Rugby), 5 Stuart Grimes (Newcastle Falcons), 4 Scott Murray (Edinburgh Rugby), 3 Bruce Douglas (The Borders), 2 Gordon Bulloch (Glasgow Rugby), 1 Tom Smith (Northampton Saints)
Replacements:16 Steve Scott (The Borders), 17 Gavin Kerr (Leeds Tykes), 18 Jason White (Glasgow Rugby), 19 Jon Petrie (Glasgow Rugby), 20 Mike Blair (Edinburgh Rugby), 21 Gordon Ross (Leeds Tykes), 22 Andy Craig (Orrell)