Today
Arsenal (2) v Wimbledon (13)
Teenager Matthew Upson is set to make only his fifth Premiership start of the season as centre-backs Martin Keown and Steve Bould are suspended. Lee Dixon is back in the squad but is rated doubtful to start the game due to a continuing hamstring problem. Gilles Grimandi is also out, so Remi Garde could continue at full-back.
Wimbledon are without new skipper Robbie Earle who is sidelined by a broken toe which could rule him out for the remainder of the season, also jeopardising his World Cup Finals plans with Jamaica in France.
Last Season: Arsenal 0-1 Wimbledon, Wimbledon 2-2 Arsenal
Last five league matches - Arsenal WWWWW, Wimbledon LDDWD
Top Scorers: Dennis Bergkamp (Arsenal) 20; Carl Leaburn, Jason Euell (Wimbledon) 8
Match Odds: H 1-3 A 13-2 D 10-3
Referee: P Jones (Loughborough)
Barnsley (19) v Tottenham (17)
Barnsley's Ashley Ward (thigh strain) is a major doubt and Jan Aage Fjortoft is set to play with bruised ribs but Ales Krizan (hamstring) and Peter Markstedt (neck) are sidelined and Darren Sheridan, Georgi Hristov, Jovo Bosancic and Chris Morgan are suspended.
Les Ferdinand is set to start for Spurs after proving his fitness to coach Christian Gross. He is likely to replace Chris Armstrong and partner Jurgen Klinsmann in attack. Darren Anderton will be on the bench again, even though Moussa Saib is ruled out, as Gross does not yet feel the England midfielder is fully match fit.
Last season: No corresponding fixtures
Last five league matches - Barnsley LLLWL, Tottenham DWDLD
Top Scorers: Jan Aage Fjortoft (Barnsley) 18; David Ginola (Tottenham) 9
Match Odds: H 11-8 A 6-4 D 12-5
Referee: M J D Bodenham (East Looe)
Bolton (18) v Leeds (5)
Bolton have problems in defence, where long-term injury victims Gerry Taggart, Mike Whitlow and Robbie Elliott could be joined on the sidelines by young leftback Hasney Aljofree, who suffered a leg injury in the 4-0 defeat at Derby on Monday. Jimmy Phillips could be recalled and Mark Fish is fit after an ankle scare. Scott Sellars (back) and Dean Holdsworth (hamstring) are out and Bob Taylor is a doubtful starter.
Leeds will be without Portuguese midfielder Bruno Ribeiro for the rest of the season after he broke down in training yesterday with a recurrence of his groin injury. Defender David Robertson is back in the squad for the first time since a cartilage operation two months ago.
Last Season: No corresponding fixtures
Last five league matches - Bolton WLDWL, Leeds WLWWL
Top Scorers: Nathan Blake (Bolton) 12; Jimmy Floyd Hasselbaink (Leeds) 19
Match Odds: H 6-4 A 11-8 D 12-5
Referee: J T Winter (Stockton-on-Tees)
Crystal Palace (20) v Derby (7)
Palace hope Jamie Fullarton, who suffered a badly gashed leg that required several stitches, will win his fitness battle and face Jim Smith's men at Selhurst Park.
Derby skipper Igor Stimac returns from shoulder and back injuries and Lee Carsley has recovered from illness. Stefano Eranio is doubtful with a groin strain and Mart Poom and Dean Sturridge have been laid low with a chest infection and heavy cold respectively. Jacob Laursen (knee) and Darryl Powell (ankle) are definitely out.
Last Season: No corresponding fixtures
Last five league matches - Crystal Palace LWLLL, Derby LLLDW
Top Scorers: Matt Jansen (Crystal Palace) 14; Paulo Wanchope (Derby) 16
Match Odds: H 7-4 A 6-5 D 12-5
Referee: P E Alcock (Redhill)
Everton (16) v Leicester (10)
Everton have Nicky Barmby and teenager Danny Cadamarteri serving one-match bans. Norwegian keeper Thomas Myhre and England Youth defender Michael Ball have missed training this week with flu, but both should be fit to play. Dave Watson is still out with a knee problem.
Neil Lennon loses his ever-present record for Leicester this season because of a one-match ban. Garry Parker replaces the Northern Ireland international in midfield, while defender Steve Walsh comes in for Spencer Prior (ribs).
Last Season: Everton 1-1 Everton, Everton 1-2 Leicester
Last five league matches - Everton WLDWD, Leicester LLDWD
Top Scorers: Duncan Ferguson (Everton) 10; Ian Marshall (Leicester) 8
Match Odds: H 10-11 A 12-5 D 12-5
Referee: S J Lodge (Barnsley)
Man Utd (1) v Newcastle (15)
United will be without Ryan Giggs (hamstring) and Ronny Johnsen (ankle ligaments) but they could be fit for the trip to Crystal Palace on Monday week.
Newcastle boss Kenny Dalglish has centre-half Darren Peacock definitely out of contention with a calf strain. Centre-half Steve Howey and England B call up Steve Watson are both unlikely to start but Italian defender Alessandro Pistone has recovered from tonsilitis and is likely to at least be on the bench.
Last Season: Man Utd 0-0 Newcastle, Newcastle 5-0 Man Utd
Last five league matches - Man Utd DLWWD, Newcastle LLDLW
Top Scorers: Andy Cole (Man Utd) 23; Gary Speed (Newcastle) 8
Match Odds: H 4-9 A 13-2 D 5-2
Referee: U D Rennie (Sheffield)
Southampton (12) v Aston Villa (9)
Defender Ken Monkou is likely to return alongside Richard Dryden for Southampton with Norwegian defender Claus Lundekvam ruled out by a one-match ban. England under-21 striker Kevin Davies is sidelined after having six stitches in a knee injury following last weekend's defeat against Wimbledon while midfielder David Hughes is battling to overcome a leg injury.
Aston Villa midfielder Mark Draper is bidding for a recall. He was left on the bench for last Saturday's 2-1 win at Coventry but could return if boss John Gregory opts to strengthen his midfield at the expense of striker Savo Milosevic.
Last Season: Southampton 0-1 Aston Villa, Aston Villa 1-0 Southampton
Last five league matches - Southampton LWLLD, Aston Villa LWWWW
Top Scorers: Kevin Davies (Southampton) 12; Dwight Yorke (Aston Villa) 13
Match Odds: H 6-4 A 6-4 D 11-5
Referee: A B Wilkie (Chester-le-Street)
West Ham (8) v Blackburn (6)
John Moncur is sidelined by a sprained ankle sustained in training this week. Stan Lazaridis has recovered from hamstring problems and John Hartson is playing his last game of the season before starting a suspension for his sending off against Derby.
Chris Sutton has recovered from a foot injury and returns for Blackburn at the expense of Martin Dahlin. Damien Duff (groin) is a doubtful starter and skipper Tim Sherwood (hamstring) is a slight doubt while defenders Callum Davidson, Tore Pedersen and Marlon Broomes have all joined Tim Flowers on the long-term injury list.
Last Season: West Ham 2-1 Blackburn, Blackburn 2-1 West Ham
Last five league matches - West Ham WWLDD, Blackburn LWLLL
Top Scorers: John Hartson (West Ham) 22; Chris Sutton (Blackburn) 20
Match Odds: H Evens A 2-1 D 5-2
Referee: P A Durkin (Portland)
Sunday
Coventry (11) v Liverpool (3)
Coventry have a midfield crisis with George Boateng (dead leg) and Gavin Strachan (twisted knee) doubtful and Paul Telfer missing through suspension. Paul Williams, Willie Boland and Martin Johansen come into contention.
Liverpool have major doubts over ankle injury victims Steve McManaman, Steve Harkness and David Thompson, who face late fitness tests.
Last Season: Coventry 0-1 Liverpool, Liverpool 1-2 Coventry
Last five league matches - Coventry DWDLD, Liverpool WDWDW
Top Scorers: Dion Dublin (Coventry) 20; Michael Owen (Liverpool) 20
Match Odds: H 13-8 A 5-4 D 12-5
Referee: N S Barry (Scunthorpe)
Chelsea (4) v Sheff Wed (14)
Dmitri Kharine has recovered from a knee injury and will replace Ed De Goey in goal for Chelsea while Dan Petrescu may be fit to return after a bout of flu. Roberto Di Matteo is available again after completing a suspension but Dennis Wise may rest his toe and thigh problems. David Lee could again replace Frank Leboeuf at the heart of defence.
Peter Atherton returns to skipper Wednesday after completing a two-match ban. Graham Hyde returns from suspension but Macedonian international defender Goce Sedloski is out for the rest of the season after an operation this week to remove knee cartilage.
Last Season: Chelsea 2-2 Sheff Wed, Sheff Wed 0-2 Chelsea
Last five league matches - Chelsea WLWLW, Sheff Wed LLWLD
Top Scorers: Gianluca Vialli (Chelsea) 18; Paolo Di Canio (Sheff Wed) 13
Match Odds: H 4-6 A 10-3 D 5-2
Referee: G S Willard (Worthing)
Odds supplied courtesy of William Hills