8 mins Sheringham replaces injured Roy Keane and pushes up alongside Cole with Ole Gunnar Solskjaer dropping back into midfield.
10 Cole spins away from Nikos Dabizas to feed Sheringham, who plays a perfectly-executed one-two with Paul Scholes before sliding the ball past the hopelessly exposed Steve Harper to make it 1-0.
24 Sheringham finds a yard of space to get on the end of David Beckham's inswinging free-kick from the left but glances his header well wide.
34 Cole runs on to Solskjaer's pass and lifts the ball over Harper, but his effort lacks pace and Dabizas is able to clear.
39 Sheringham meets Gary Neville's near-post cross with a firm downward header and is only just wide.
45 Cole turns Dabizas easily only to be denied by Laurent Charvet's tackle, but when Harper's clearance reaches the striker he fires towards goal but cannot test the keeper.
53 Solskjaer intercepts Dabizas' pass and feeds Sheringham, who lays the ball back perfectly for Scholes to fire past Harper.
60 Yorke replaces Cole and links up with Sheringham.
62 Giggs crosses from the left and Yorke sends a free header a yard over.
78 Giggs bursts through from central midfield and rolls the ball into Sheringham's path, but his delicate chip drops on to the bar with Harper beaten.