SOCCER:AS Roma have undergone a dramatic transformation since losing the first leg and travel to Ukraine for the return in confident mood.
Roma have gained a new manager, won two matches, drawn one and lost one since their shock defeat last month by Shakhtar.
Shakhtar will be without central defender Olexandr Kucher and Brazilian midfielder Fernandinho through injury.
Roma playmaker Jeremy Menez is suspended, as is right back Marco Cassetti. Nicolas Burdisso may shift across from centre half. Striker Adriano is still out with a shoulder problem and broken arm.