Roche ‘steps up’ for gene therapy with $4.3 bn Spark bet
Swiss-based pharma company buying spark as rivals move aggressively into gene therapy
More firms weigh IPOs as biotech fever reaches Europe
Top candidates for a share sale include Swiss firms AC Immune and Molecular Partners
Bubble fears grow amid glut of IPOs in the US by early-stage biotechs
Dicerna Pharmaceuticals a focal point of concern as it has yet to enter clinical trials and refused to impose share sale block on major shareholders
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