Anthony Martial was a late withdrawal from the Manchester United team ahead of Thursday's Europa League last-32 second leg against FC Midtjylland at Old Trafford.
United confirmed via Twitter just before kick-off that forward Martial had pulled out of the first XI having sustained an injury in the warm-up.
His replacement was 18-year-old Marcus Rashford, making his first-team debut.
The club gave no details of Martial’s problem, but it appeared to be a hamstring issue. The Frenchman joins what is already a lengthy list of United players unavailable through injury, including captain Wayne Rooney.