France coach Bernard Laporte will give Thomas Castaignede his first start at flyhalf for six years against Romania in Bucharest on Saturday.
The 31-year-old Saracens player has won 19 of his 50 caps at flyhalf, the last against England in the 2000 Six Nations.
Since he returned to international action in November following injury, Castaignede has been selected at fullback and centre.
He made his international debut in 1995 and was arguably the world's best flyhalf at the end of the 1990s before his career was hit by injuries.
He will take over the number 10 jersey from Frederic Michalak who has been ruled out of France's June tour because of a shoulder injury suffered in the French championship final against Biarritz last Saturday.
After facing Romania, France will travel to South Africa for a single test against the Springboks in Cape Town on June 24.
Team: 15-Clement Poitrenaud; 14-Philippe Bidabe, 13-Yannick Jauzion, 12-Damien Traille, 11-Cedric Heymans; 10-Thomas Castaignede, 9-Pierre Mignoni; 8-Julien Bonnaire, 7-Remy Martin, 6-Thierry Dusautoir, 5-Fabien Pelous (cap), 4-Lionel Nallet, 3-David Attoub, 2-Raphael Ibanez, 1-Sylvain Marconnet.
Replacements: 16-Dimitri Szarzewski, 17-Vincent Debaty, 18-Jerôme Thion, 19-Imanol Harinordoquy, 20-Dimitri Yachvili, 21-David Marty, 22-Julien Laharrague.
