South Africa will field nine of their victorious World Cup final starting line-up against Wales at the Millennium Stadium.
Despite several players missing the two-match tour - South Africa meet the Barbarians at Twickenham on Saturday week - Springboks coach Jake White can still field a strong side.
World Cup-winning captain John Smit leads a team that contains just one new cap - Natal Sharks number eight Ryan Kankowski.
Smit is joined on Saturday by fellow World Cup final starters JP Pietersen, Jaque Fourie, Francois Steyn, Bryan Habana, CJ van Der Linde, Bakkies Botha, Schalk Burger and Juan Smith.
It will be South Africa's first match since they landed the Webb Ellis Trophy by beating England in Paris on October 20.
Notable absentees include full-back Percy Montgomery, half-backs Butch James and Fourie Du Preez, lock Victor Matfield and number eight Danie Rossouw.
The Wales Test will be White's final full international match in charge of the Springboks.
White has yet to make any decision about his future, although he has been linked to a possible role with England.
Wales, meanwhile, will be under the supervision of caretaker coach Nigel Davies, who hands over the reins to new boss Warren Gatland next week.
Davies on Tuesday announced a side containing one debutant - Llanelli Scarlets full-back Morgan Stoddart - while Ospreys centre Gavin Henson makes his first Wales start for more than a year.