Blackburn (10) v Reading (8)
Blackburn striker Jason Roberts is suspended after being sent off in the 1-1 draw with Tottenham last night. Matt Derbyshire or Shabani Nonda could replace Roberts with Rovers looking for a route into Europe through the Intertoto Cup. David Dunn is doubtful with a thigh problem while Zurab Khizanishvili, Robbie Savage and Steven Reid are again ruled out through injury.
Reading boss Steve Coppell is unlikely to include Steve Sidwell in his squad as he is soon to be a free agent. Glen Little (Achilles), Graeme Murty (calf), Bobby Convey (knee) and Ibrahima Sonko (knee) remain sidelined but Greg Halford has recovered from a foot injury.
Last season: No corresponding fixture
Last five league matches: Blackburn L W D W W; Reading D W W W L
Top scorers: Benni McCarthy (Blackburn) 22; Leroy Lita (Reading) 14
Match odds: H 21-20 A 19-10 D 12-5
Referee: A Wiley (Staffordshire).
Bolton (7) v Aston Villa (11)
Abdoulaye Faye and Tal Ben Haim are both expected to be passed fit. Faye, who has missed three games with an infected toe, and Ben Haim, sidelined for two matches with an injured knee, have responded well to treatment this week. That has left El-Hadji Diouf (hamstring), Nicky Hunt (calf) and Joey O'Brien (knee) as Bolton's only absentees.
Villa manager Martin O'Neill is likely to name an unchanged line-up. The former Celtic pair of Stiliyan Petrov (hamstring) and Shaun Maloney (ankle) are still battling for fitness after missing the win against Sheffield United.
Last season: Bolton 1 Aston Villa 1, Aston Villa 2 Bolton 2
Last five league matches: Bolton D L L D L; Aston Villa D W D W W
Top scorers: Nicolas Anelka (Bolton) 12; Gabriel Agbonlahor (Aston Villa) 10
Match odds: H 10-11 A 5-2 D 11-5
Referee: M Clattenburg (Co Durham).
Chelsea (2) v Everton (5)
Chelsea will be without Andriy Shevchenko (hernia), Michael Ballack (ankle), Didier Drogba (ankle), Ricardo Carvalho (knee), Arjen Robben (knee) and Scott Sinclair (foot). Midfielder Frank Lampard and goalkeeper Petr Cech, rested against Manchester United, are expected to return.
Andrew Johnson will miss the final game of Everton's season at Chelsea after having an ankle operation today. Boss David Moyes is expected to name an unchanged team against the deposed champions, with teenage strikers JamesVaughan and Victor Anichebe up front.
Last season: Chelsea 3 Everton 0, Everton 1 Chelsea 1
Last five league matches: Chelsea W D D D D; Everton D W L L W
Top scorers: Didier Drogba (Chelsea) 31; Andrew Johnson (Everton) 12
Match odds: H 1-2 A 9-2 D 13-5
Referee: M Halsey (Lancashire).
Liverpool (3) v Charlton (19)
Robbie Fowler will bring the curtain down on his Liverpool career on Sunday, but goalkeeper Jerzy Dudek will almost certainly be denied the chance to play in one final game for the club. Fowler's contract will not be renewed, while Dudek also leaves in the summer. But a groin injury sustained in training today means the Poland international is highly unlikely to be fit to face Charlton. WithJose Reina nursing a shoulder injury, the chance now is that Italian youngster Daniele Padelli will make his debut in goal.
Young Irishman Darren Randolph looks set to make his Premiership debut in goal for Charlton, with on-loan Scott Carson ineligible to play against his parent club. Full-back Ben Thatcher is available again after suspension.
Last season: Liverpool 0 Charlton 0, Charlton 2 Liverpool 0
Last five league matches: Liverpool D W W L L; Charlton D L D L L
Top scorers: Peter Crouch (Liverpool) 18; Darren Bent (Charlton) 14
Match odds: H 4-11 A 6-1 D 3-1
Referee: D Gallagher (Oxfordshire).
Man Utd (1) v West Ham (17)
Sir Alex Ferguson has indicated either Cristiano Ronaldo or Wayne Rooney could start on the bench. With Gary Neville (ankle) and Louis Saha (knee) virtually out of contention for next week's FA Cup final, places at the Wembley showpiece are up for grabs, with Alan Smith and Wes Brown in particular hoping to impress.
West Ham boss Alan Curbishley has no fresh injury worries. Luis Boa Morte appears set to continue on the left of midfield but inspirational striker Carlos Tevez could be playing his final game for the club as his future remains in doubt.
Last season: Man Utd 1 West Ham 0, West Ham 1 Man Utd 2
Last five league matches: Man Utd W D W W D; West Ham L L W W W
Top scorers: Cristiano Ronaldo & Wayne Rooney (Man Utd) 23; Bobby Zamora (West Ham) 11
Match odds: H 8-13 A 4-1 D 23-10
Referee: M Atkinson (W Yorkshire).
Middlesbrough (12) v Fulham (15)
Jonathan Woodgate has been named in the Middlesbrough squad despite suffering from a knee problem. The defender will go under the knife on Monday for an exploratory operation on his left knee after playing with a 'niggle' for the past few weeks. Fellow defender Andrew Taylor has already had an operation on a toe condition and misses out with Emanuel Pogatetz expected to slot in at left-back. Chris Riggott is favourite to replace the Austrian and partner Woodgate in the centre. Robert Huth (ankle) is unavailable.
Midfielders Michael Brown and Papa Bouba Diop are suspended, left-back Franck Queudrue has recovered from his ankle injury but central defender Ian Pearce remains in the treatment room with a calf problem. Italian striker Vincenzo Montella is out with a groin injury.
Last season: Fulham 1 Middlesbrough 0, Middlesbrough 3 Fulham 2
Last five league matches: Middlesbrough L L D L W; Fulham L L D L W
Top scorers: Mark Viduka (Middlesbrough) 17; Brian McBride (Fulham) 12
Match odds: H 5-6 A 11-4 D 11-5
Referee: M Riley (W Yorkshire).
Portsmouth (9) v Arsenal (4)
Arsenal have a concern over striker Emmanuel Adebayor (groin), Freddie Ljungberg returns from his hamstring problem, but fellow midfielder Tomas Rosicky is unavailable because of a similar problem. Gilberto will be rested, along with Jens Lehmann, so Manuel Almunia will be in goal. Captain Thierry Henry (groin and stomach), Robin van Persie (broken foot) and Theo Walcott (shoulder) are all sidelined.
Former Arsenal defender Lauren has been added to Portsmouth's casualty list. The Cameroon star has a foot injury and joins another ex-Gunner Sol Campbell (Achilles) and skipper Dejan Stefanovic (thigh) on the sidelines. Midfielders Matt Taylor (ankle) and Richard Hughes (knee) continue to be doubtful after missing the game at Everton but Pedro Mendes is back in the squad and could play his first game since an ankle operation in February.
Last season: Portsmouth 1 Arsenal 1, Arsenal 4 Portsmouth 0
Last five league matches: Portsmouth L W D W L; Arsenal W W D W D
Top scorers: Kanu (Portsmouth) 12; Robin Van Persie (Arsenal) 13
Match odds: H 6-4 A 13-10 D 12-5
Referee: G Poll (Hertfordshire).
Sheff Utd (16) v Wigan (18)
Neil Warnock looks set to ease the pressure on new England B call-up Phil Jagielka by naming a substitute goalkeeper for the Blades. Ian Bennett is the man expected to take a place on the bench as back-up for first-choice Paddy Kenny. Nick Montgomery (shoulder) is Warnock's only major fitness worry.
Left-back Leighton Baines is a major doubt after injuring a hip in last week's 1-0 defeat to Middlesbrough and has not trained all week. David Unsworth, signed on a free transfer from the Blades in January, is poised to step in. Latics captain Arjan de Zeeuw (ankle) is also a doubt.
Last season: No corresponding fixture
Last five league matches: Sheff Utd W L D W L; Wigan D D L L L
Top scorers: Rob Hulse, Jonathan Stead & Luton Shelton (Sheff Utd) 8; Caleb Folan (Wigan) 14
Match odds: H 6-5 A 17-10 D 23-10
Referee: M Dean (Wirral).
Tottenham (6) v Man City (14)
Spurs hope Jermaine Jenas recovers from back spasms in time to face City. He missed the Blackburn clash along with Ricardo Rocha (ankle), Mido (groin) and Young-Pyo Lee (knee). Steed Malbranque picked up a knock in the 1-1 draw and was taken off in the first half.
Stephen Jordan could be handed a farewell Manchester City appearance. He has been informed his Blues contract will not be renewed this summer but with Michael Ball suspended for the White Hart Lane trip, he would be the automatic choice to fill the left-back slot. With Micah Richards still on the injured list and Joey Barton banned by his own club, Pearce is not expected to make many changes from the side beaten by Manchester United last weekend.
Last season: Tottenham 2 Man City 1, Man City 0 Tottenham 2
Last five league matches: Tottenham L D D W W; Man City D L D L L
Top scorers: Dimitar Berbatov (Tottenham) 22; Joey Barton (Man City) 7
Match odds: H 1-2 A 5-1 D 12-5
Referee: S Bennett (Kent).
Watford (20) v Newcastle (13)
Watford welcome back defender Clarke Carlisle from suspension and he is expected to replace young Frenchman Cedric Avinel in central defence. On-loan Manchester United goalkeeper Ben Foster plays his final game for the club, and Adrian Mariappa could come in for Lloyd Doyley in defence, with Tamas Priskin preferred to Darius Henderson in attack. Jay DeMerit is on approved absence and forward Hameur Bouazza has been granted compassionate leave. Damien Francis, Gareth Williams and Moses Ashikodi remain sidelined with injury.
Midfielders Scott Parker (hernia) and Damien Duff (foot) are out for United, Shay Given (groin) and Steven Taylor (thigh) are rated 50-50, but Emre (ankle) and Antoine Sibierski (broken arm) will both be missing.
Last season: No corresponding fixture
Last five league matches: Watford W L D L W; Newcastle D L D L L
Top scorers: Will Hoskins (Watford) 16; Obafemi Martins (Newcastle) 17
Match odds: H 6-4 A 6-4 D 21-10
Referee: R Styles (Hampshire).