Open Orphan

Ireland’s Mr IPO and his plans to make more companies public

Cathal Friel shows no sign of slowing down after a busy week which saw him sell his remaining stake in Hvivo

Tue Jul 30 2024 - 05:54

Hvivo chairman Cathal Friel sells remaining shares for €7.3m

Businessman oversaw the initial flotation in 2019 of clinical trials group that became Hvivo

Tue Jul 23 2024 - 16:16

Pharmaceutical services company Hvivo sells almost 30m placing shares

New and existing institutional investors indicated demand for shares was in excess of those available

Wed Feb 14 2024 - 15:40

Hvivo signs €7.3m contract to test cold virus treatment

Pharmaceutical services company is testing drug for human rhinovirus in human challenge trial

Tue Jan 02 2024 - 07:42

Poolbeg Pharma uses AI to identify potential drug targets for flu treatment

Biopharmaceutical company hails work with CytoReason as ‘significant breakthrough’

Thu Jun 29 2023 - 07:07

Hvivo inks €5.9m contract with Asia-Pacific biotech to test vaccine

Deal is Dublin-listed pharma company's first in the region in over 10 years

Wed Jan 04 2023 - 12:12

Poolbeg Pharma sees artificial intelligence breakthrough in RSV drug discovery

Company has been working with OneThree Biotech to us artificial intelligence to identify novel drug targets for RSV treatment

Tue Nov 08 2022 - 08:11

Open Orphan appoints Stephen Pinkerton as chief financial officer

Leo Toole has stepped down from the board and CFO role to pursue other interests, company announced on Monday

Tue Oct 18 2022 - 07:17

Open Orphan subsidiary signs deal with global pharma company

Deal will see hVivo manufacture virus for use in human challenge studies

Wed May 04 2022 - 08:29

Open Orphan subsidiary signs €6m contract for respiratory study

Company expects revenues from the contract to be recognised across 2022 and 2023

Fri Mar 25 2022 - 07:30

Open Orphan appoints Yamin Khan as new chief executive

Cathal Friel to continue in executive chairman role under new management structure

Thu Feb 24 2022 - 10:24

Potential RSV vaccine achieves regulatory step in US

Bavarian Nordic vaccine candidate used hVivo challenge trial to gather data

Tue Feb 22 2022 - 07:47

Open Orphan subsidiary wins $13.4m contract with US biotech company

Executive chairman Cathal Friel said Hvivo expects to sign a number of similar contracts

Fri Dec 10 2021 - 07:22

Open Orphan subsidiary signs €6.7m contract for flu study

Influenza could be a major global issue due to low immunity caused by reduced infection

Mon Sept 20 2021 - 08:13

Open Orphan wins €9.5m asthma contract with major pharma company

Study is being carried out under asthma human challenge study model

Tue Aug 24 2021 - 08:51

Open Orphan subsidiary develops human study for malaria

Healthy volunteers are administered a pathogenic or virulent strain of virus

Mon Aug 09 2021 - 07:18

Open Orphan spin-out Poolbeg to raise £25m in IPO

Infectious diseases specialist to list in London

Wed Jul 14 2021 - 19:31

Open Orphan pharmaceutical company expands Covid-19 trial

Challenge study is providing valuable insight into biology of the virus, firm says

Wed Jul 14 2021 - 07:23

Open Orphan spin-out Poolbeg Pharma to list on London market

Company will use money from listing to meet costs for flu drug trials, develop assets

Thu Jun 17 2021 - 08:03

Open Orphan gets approval to reduce capital ahead of spin-out

Company says reduction of capital will allow it to return value to its shareholders

Wed May 19 2021 - 09:22

Open Orphan subsidiary signs £3m contract for Covid-19 study

hVivo will develop a new SARS-CoV-2 challenge virus based on new emerging variants

Mon May 10 2021 - 07:38

Open Orphan plans for possible spin-out of non-core assets

Company says HVO-001 could be included as part of potential demerger

Tue Apr 13 2021 - 16:57

Open Orphan subsidiary wins €7.5m contract to run study

Contract with US biotechnology company concerns a respiratory syncytial virus

Fri Mar 26 2021 - 07:38

Open Orphan gets final go-ahead for Covid-19 human trial

Irish clinical trials group will deliberately infect healthy young volunteers with virus

Wed Feb 17 2021 - 17:19

Open Orphan company successfully completes nasal spray study

Prophylactic spray could be used against Covid-19

Wed Dec 23 2020 - 10:56

Open Orphan renews contract with major pharma company

Dublin-listed pharmaceutical services company says new deal will run for another year

Tue Dec 22 2020 - 15:50

Open Orphan gets green light for Covid-19 nasal vaccine trial

Vaccine could be one of the first to provide long-term immunity from Covid-19

Mon Dec 14 2020 - 07:55

Venn Life Sciences wins another Covid-19 drug study

Open Orphan subsidiary to manage Phase 2 clinical trial for European pharma company

Mon Dec 07 2020 - 08:15

Open Orphan subsidiary takes lead role on guidelines for human challenge agents

Guidelines will cover manufacture of agents for use in controlled infection studies

Thu Nov 19 2020 - 07:50

Coronavirus vaccine: ‘By next summer, Covid will be close to a bad memory’

‘All we have at this point is a very promising press release. But the signs are very promising’

Sat Nov 14 2020 - 06:00

Open Orphan signs two year contract with German pharma company

Contract guarantees annual revenue for Dublin listed company

Fri Oct 30 2020 - 09:48

Open Orphan subsidiary hVivo signs deal for Covid-19 challenge study

Contract with UK government could be worth up to £10m

Tue Oct 20 2020 - 07:49

Open Orphan eyes profitability as it reports £4.1m ebitda loss

Company led by Cathal Friel recorded revenues of £7.1m for its first half

Wed Sept 30 2020 - 08:36

HSE to provide extra 1,500 hospital beds as part of €600m winter plan

Officials warn Covid infections across country ‘a week or two’ behind Dublin

Thu Sept 24 2020 - 01:15